DetoxTo prove he isn't addicted to Vicodin, House agrees to go off the pills for a week while treating a teen with internal bleeding.
– A legendary jazz musician signs a "Do Not Resuscitate" order, which House promptly ignores. index of house m.d. season 1
| # | Episode Title | Original Airdate | Key Medical Mystery | Iconic House Moment | | :--- | :--- | :--- | :--- | :--- | | 1 | | Nov 16, 2004 | A kindergarten teacher becomes aphasic and seizures. | House uses a cane; first "It’s not lupus." | | 2 | Paternity | Nov 23, 2004 | A teen with night terrors and double vision. | House treats a minor without parental consent. | | 3 | Occam’s Razor | Nov 30, 2004 | A man has a cold that won’t go away + organ failure. | "The simplest explanation is usually correct." | | 4 | Maternity | Dec 7, 2004 | Newborns in the hospital nursery get a mysterious illness. | House vs. Cuddy over quarantine. | | 5 | Damned If You Do | Dec 14, 2004 | A nun suffering from an allergic reaction to a Santa Claus statue. | First appearance of the portable MRI concept. | | 6 | The Socratic Method | Dec 21, 2004 | A schizophrenic homeless woman with blood clots. | House steals a patient from the ER. | | 7 | Fidelity | Dec 28, 2004 | A woman in a coma despite sleeping sickness treatment. | The controversial "wake-up" treatment (African sleeping sickness). | | 8 | Poison | Jan 25, 2005 | A high school student collapses with acute poisoning. | House investigates the victim’s home. | | 9 | DNR | Feb 1, 2005 | A famous jazz trumpeter with paralysis who wants a Do Not Resuscitate order. | House defies a DNR order. | | 10 | Histories | Feb 8, 2005 | A homeless woman with rabies-like symptoms. | Surprisingly emotional ending; Wilson’s backstory shines. | | 11 | Detox | Feb 15, 2005 | A teen in a car crash refuses to detox from drugs. | House bets Cuddy he can go one week without Vicodin. | | 12 | Sports Medicine | Feb 22, 2005 | A steroid-using athlete’s bone suddenly dissolves. | House uses a cadaver arm to break into a locker. | | 13 | Cursed | Mar 1, 2005 | A boy who played with a Ouija board develops lesions. | First episode focusing on House’s own leg pain origin. | | 14 | Control | Mar 15, 2005 | A high-powered CEO has a heart attack with no risk factors. | House fires a patient for lying about bulimia. | | 15 | Mob Rules | Mar 22, 2005 | A mobster with hepatitis fails to wake up from a coma. | Chase’s Catholic guilt is explored. | | 16 | Heavy | Mar 29, 2005 | An obese 8-year-old girl with heart problems. | House accuses the mother of Munchausen by proxy. | | 17 | Role Model | Apr 12, 2005 | A senator running for president collapses with seizures. | First major "House is wrong" twist. | | 18 | Babies & Bathwater | Apr 19, 2005 | A pregnant woman with terminal cancer must choose: save herself or the baby. | Cuddy considers adopting the baby. | | 19 | Kids | May 3, 2005 | A 12-year-old competitive swimmer collapses with meningitis. | Vogler (Chi McBride) begins his war on House. | | 20 | Love Hurts | May 10, 2005 | A football player collapses after scoring a touchdown. | House struggles with attraction to a new clinic worker. | | 21 | Three Stories | May 17, 2005 | Masterpiece. House lectures students on three leg-pain cases. | Emmy-winning episode. Explains House’s cane and ex-girlfriend Stacy. | | 22 | Honeymoon | May 24, 2005 | Stacy’s husband has sudden muscle weakness. | House offers to kill Stacy’s husband to get her back. | DetoxTo prove he isn't addicted to Vicodin, House
DNRA legendary jazz musician signs a "Do Not Resuscitate" order. House ignores it to save his life, leading to a massive legal and ethical debate. | House uses a cane; first "It’s not lupus