To fix the Virtual USB Bus Error 39 in Mastercam (X7 through 2022 versions), you typically need to
Contact your Mastercam Reseller with the following info: Windows version (e.g., Win11 22H2), Mastercam build number, and a screenshot of Device Manager showing Code 39. They can provide version-specific hotfixes. mastercam x72022 virtual usb bus error 39 fix
He tried the usual exorcisms:
Happy machining.