Dominic Purcell’s Lincoln Burrows is the catalyst for Season 5. After receiving a mysterious photo from T-Bag, Lincoln travels to a war-torn Sana'a to find his brother.

While fans spent years thinking Michael Scofield’s story ended with a final sacrifice, Season 5 (the "Resurrection" revival) proved that getting out of a Yemeni hellscape requires more than just tattoos—it requires the original heavy hitters. If you’re looking back at the 2017 revival, 1. Wentworth Miller (Michael Scofield / Kaniel Outis)

No revival would be complete without the show's most notorious antagonist. Knepper's T-Bag is released from Fox River at the start of Season 5 and receives a mysterious letter that sets the plot in motion. His character's evolution—including a surprising connection to a new character—remains a highlight for many fans. Mark Feuerstein (Jacob Ness)

: Sara's new husband and a professor, whose secret identity as the rogue CIA operative "Poseidon" makes him the season's primary villain. Inbar Lavi as